Passive immunisation against tetanus
Adult: For the postexposure prophylaxis of patients with tetanus-prone injuries, those who are unimmunised or inadequately vaccinated against tetanus, whose tetanus immunisation history is unknown or uncertain, whose last dose of tetanus vaccine has elapsed for >10 years, or with impaired immunity: In conjunction with a tetanus toxoid-containing vaccine (refer to specific country guideline): 250 international units via deep IM inj. If >24 hours have passed since injury, if the patient is at risk of heavy contamination, or after burns: 500 international units as a single dose via deep IM inj. Administer large volumes (>5 mL) in divided doses at different sites.
Child: Same as adult dose. Administer large volumes (>2 mL) in divided doses at different sites.
Child: Same as adult dose. Administer large volumes (>2 mL) in divided doses at different sites.
Intramuscular
Tetanus
Adult: For the treatment of cases in combination with anti-infective agents, sedatives, and muscle relaxants: 3,000-6,000 international units via deep IM inj. Dosing frequency, interval of administration, and duration of treatment may vary among countries and individual products (refer to country-specific guidelines).
Child: There is limited information regarding the use of this drug in this population, treatment recommendations may vary among countries and individual products (refer to country-specific guidelines).
Child: There is limited information regarding the use of this drug in this population, treatment recommendations may vary among countries and individual products (refer to country-specific guidelines).